Trifluoroacetic acid → HCID 86727486, compound

Participants

Reaction Steps

A solution of 3-(7-benzyloxy-4-methyl-3-oxo-2,3,4,10-tetrahydro-9-oxa-1,2,4a-triaza-phenanthren-6-ylamino)-azetidine-1-carboxylic acid tert-butyl ester (0.028 g, 0.057 mmol) in TFA (0.5 mL) and DCM (3 mL) was stirred at rt for 2 h. The solvent was removed in vacuo and the residue was purified by preparative HPLC (Table 3, Method 18) to give 6-(azetidin-3-ylamino)-7-benzyloxy-4-methyl-2,10-dihydro-9-oxa-1,2,4a-triaza-phenanthren-3-one trifluoroacetic acid (0.013 g, 58%). LC/MS (Table 1, Method 5) Rt=2.201 min; MS m/z: 394 [M+H]+

Provenance & Evidence