HRID519273

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID817620

5-Bromo-2-nitropyridine

C5H3BrN2O2

结构：C[C@@H]1CN(Cl)[C@@H](C)CN1C(=O)OC(C)(C)C

HCID86683704

未命名化合物

PRODUCTS

生成物

结构：C[C@@H]1CN(c2ccc([N+](=O)[O-])nc2)[C@@H](C)CN1C(=O)OC(C)(C)C

HCID86683703

未命名化合物

收率 75%

PROCEDURE

实验过程

Following the procedures as described for compound 108a, (2R,5S)-tert-butyl 4-chloro-2,5-dimethylpiperazine-1-carboxylate (1.5 g, 6.0 mmol) and 5-bromo-2-nitropyridine (1212 mg, 6.0 mol) were reacted to give 104a as a yellow solid (1500 mg, 75%). LCMS: [M+H]+ 337. See FIG. 4.

WORKUP

后处理

customwere reacted