反应详情

(S)-7-[(4′-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-quinoline-3-carboxylic acid (1-pyridin-2-yl-propyl)-amide (67 mg) was dissolved in 5 ml of ethyl acetate, and ethanesulfonic acid (13 mg, 1 equivalent) was added as a solution in 1.5 ml of ethyl acetate. After 60 min, the mixture was concentrated under vacuum to afford 80 mg of the title compound as a yellow solid.

1. concentrationthe mixture was concentrated under vacuum