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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 520241Generated: October 29, 2026

HCID 14853161, compound → HCID 118590169, compound

https://huagongshe.com/reaction/520241

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 14853161HCID 14853161—
Reactant3-(4-isothiocyanatophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazoleHCID 118590171—
ProductHCID 118590169HCID 118590169—

Reaction Steps

The title compound was prepared with 2-amino-2-(2-chlorophenyl)ethanol and 3-(4-isothiocyanatophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazole and isolated as a white solid (1.48 g, quantitative): 1H NMR (300 MHz, CDCl3) δ 8.07 (s, 1H), 7.77-7.55 (m, 2H), 7.41-7.23 (m, 3H), 7.21 (d, J=8.5 Hz, 2H), 6.81 (dd, J=8.7, 2.6 Hz, 2H), 6.65 (d, J=6.8 Hz, 6H), 5.40 (s, 1H), 3.39 (qd, J=11.6, 4.9 Hz, 2H); ESIMS m/z 518 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09326516B2
Source datasetuspto-grants-2016_05
ORD IDord-85c2fd050add42f6bdf85739d2ca07e1
Source noteuspto-grants-2016_05