3-Amino-3-(4-methylphenyl)propan-1-ol → HCID 118590125, compound

HRID 520244Notes

Reaction equation

HRID 520244 reaction equation
[NH2:1][CH:2]([C:6]1[CH:11]=[CH:10][C:9]([CH3:12])=[CH:8][CH:7]=1)[CH2:3][CH2:4][OH:5].[N:13]([C:16]1[CH:21]=[CH:20][C:19]([C:22]2[N:26]=[CH:25][N:24]([C:27]3[CH:32]=[CH:31][C:30]([O:33][C:34]([F:37])([F:36])[F:35])=[CH:29][CH:28]=3)[N:23]=2)=[CH:18][CH:17]=1)=[C:14]=S>>[C:9]1([CH3:12])[CH:8]=[CH:7][C:6]([CH:2]2[CH2:3][CH2:4][O:5][C:14]([NH:13][C:16]3[CH:17]=[CH:18][C:19]([C:22]4[N:26]=[CH:25][N:24]([C:27]5[CH:32]=[CH:31][C:30]([O:33][C:34]([F:37])([F:35])[F:36])=[CH:29][CH:28]=5)[N:23]=4)=[CH:20][CH:21]=3)=[N:1]2)=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 177503113-Amino-3-(4-methylphenyl)propan-1-olHCID 1185901653-(4-Isothiocyanatophenyl)-1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole

Product 1

HCID 118590125HCID 118590125, compound

Procedure

The title compound was prepared with 3-amino-3-(p-tolyl)propan-1-ol and 3-(4-isothiocyanato-phenyl)-1-(4-trifluoromethoxy-phenyl)-1H-1,2,4-triazole and isolated as an off-white solid (0.020 g, 9%).

Sources & evidence

ORD record
ord-9c9b229c37be48a5a3b6c77f2f6d3727
Source dataset
uspto-grants-2016_05
Patent number
US09326516B2

Reaction notes

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