1-(2-Methoxyphenyl)piperazine → 2-ethyl-3-(2-(4-(2-methoxyphenyl)piperazine-1-yl)ethyl)quinazoline-4(3H)-one

HRID 520289Notes

Reaction equation

HRID 520289 reaction equation
[CH2:1]([C:3]1[N:12]([CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][N:18]([C:21]3[CH:26]=[CH:25][CH:24]=[C:23](C(F)(F)F)[CH:22]=3)[CH2:17][CH2:16]2)[C:11](=[O:31])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1)[CH3:2].[CH3:32][O:33]C1C=CC=CC=1N1CCNCC1>>[CH2:1]([C:3]1[N:12]([CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][N:18]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[O:33][CH3:32])[CH2:17][CH2:16]2)[C:11](=[O:31])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 668251862-ethyl-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl)quinazoline-4(3H)-one

Product 1

HCID 569442102-ethyl-3-(2-(4-(2-methoxyphenyl)piperazine-1-yl)ethyl)quinazoline-4(3H)-one

Procedure

This compound was prepared in compliance with the procedure described in 7d, using 1-(2-methoxyphenyl)piperazine instead of 1-(3-(trifluoromethyl)phenyl)piperazine.

Workup

  1. customThis compound was prepared in compliance with the procedure

Sources & evidence

ORD record
ord-c314844079e84f80aa26110c5bac56a9
Source dataset
uspto-grants-2016_05
Patent number
US09326984B2

Reaction notes

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