HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 6-Acetamido-4-(3'-trifluoromethylanilino)quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,6-diamine | HCID 5328188 | — |
| Product | 6-Acetamido-4-(3'-trifluoromethylanilino)quinazoline | HCID 19963208 | 87% |
Reaction Steps
Using an analogous procedure to that described in Example 11, 6-amino-4-(3'-trifluoromethylanilino)quinazoline was reacted with acetic anhydride to give 6-acetamido-4-(3'-trifluoromethylanilino)quinazoline in 87% yield as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616582 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-aadb44704bc3403699fa55d4ae2317f2 |
| Source note | uspto-grants-1997_04 |