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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52044Generated: October 26, 2026

3-Aminophenol → 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline

https://huagongshe.com/reaction/52044

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-AminophenolHCID 11568—
Reactant4-Chloro-6,7-dimethoxyquinazolineHCID 2769364—
Product4-(3-Hydroxyanilino)-6,7-DimethoxyquinazolineHCID 568792%

Reaction Steps

Using an analogous procedure to that described in Example 68, 4-chloro-6,7-dimethoxyquinazoline was reacted with 3-aminophenol to give 4-(3'-hydroxyanilino)-6,7-dimethoxyquinazoline in 92% yield, m.p. 256°-257° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616582
Source datasetuspto-grants-1997_04
ORD IDord-1d6caa26a41b4f4d860feae9ccdb89b0
Source noteuspto-grants-1997_04