HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-3-(2-acetoxyethylthio)propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-3-(2-hydroxyethylthio)propionamide | HCID 67725561 | — |
| Product | N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-3-(2-acetoxyethylthio)propionamide | HCID 67725579 | 87% |
Reaction Steps
Following a procedure similar to that described in Example 2, but using N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-3-(2-hydroxyethylthio)propionamide (prepared as described in Example 11) and acetic anhydride as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in an 87% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616579 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-b3ffc11fad484fa4a8bc3e6181654def |
| Source note | uspto-grants-1997_04 |