HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1,4-Dimethyl-1H-pyrazole-3-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1,4-Dimethyl-1H-pyrazole-3-carboxylic acid | HCID 5325685 | — |
| Product | 1,4-Dimethyl-1H-pyrazole-3-carbonyl chloride | HCID 58356380 | — |
Reaction Steps
1,4-Dimethyl-1H-pyrazole-3-carboxylic acid (190 mg) was weighed to a round bottom flask and thionyl chloride (1 ml) was added. The reaction was heated to reflux for 6 h then overnight at RT. After this time thionyl chloride was evaporated and the residue azeotroped with toluene to afford the title compound, 200 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09326987B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-c376dc8ae7c445a988d94f474b950868 |
| Source note | uspto-grants-2016_05 |