Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52067Generated: October 26, 2026

Thiophene-3-carboxylic acid → N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]thiophene-3-carboxamide

https://huagongshe.com/reaction/52067

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiophene-3-carboxylic acidHCID 6918—
Reactant2-Buten-1-amine, 4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-, (Z)-HCID 13672473—
ProductN-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]thiophene-3-carboxamideHCID 6772596990%

Reaction Steps

Following a procedure similar to that described in Example 13, but using 4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenylamine and 3-thiophenecarboxylic acid as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as an oil in a 90% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616579
Source datasetuspto-grants-1997_04
ORD IDord-b6888ba6b8194baa83c231d6c74083f4
Source noteuspto-grants-1997_04