1-Ethynyl-4-fluorobenzene → HCID 73052686, compound

Participants

Reaction Steps

The title compound was prepared in accordance with the general method of Example 1, step 7 using (3aR,6aR)-1-(5-iodopyridin-2-yl)hexahydro-cyclopenta[b]pyrrol-2(1H)-one (100 mg, 0.305 mmol) (Example 1, step 6) and 1-ethynyl-4-fluorobenzene to yield 75 mg (77%) of the title compound as a viscous yellow oil; MS: m/e=321.2 (M+H+).

Provenance & Evidence