HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzofuran-2-sulfonyl chloride → N-(5-chloro-2-{[(5-nitro-1H-pyrazol-3-yl)methyl]thio}phenyl)-1-benzofuran-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzofuran-2-sulfonyl chloride | HCID 2795172 | — |
| Reactant | 5-chloro-2-(((5-nitro-1H-pyrazol-3-yl)methyl)thio)aniline | HCID 136372389 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(5-chloro-2-{[(5-nitro-1H-pyrazol-3-yl)methyl]thio}phenyl)-1-benzofuran-2-sulfonamide | HCID 136372390 | 71% |
Reaction Steps
Following General Procedure B, the title compound (580 mg, 71%) was prepared from 5-chloro-2-(((5-nitro-1H-pyrazol-3-yl)methyl)thio)aniline (503 mg, 1.77 mmol) and benzofuran-2-sulfonyl chloride (384 mg, 1.77 mmol) in pyridine (5 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328067B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-656478016c5e4eb491f9673d4f7ab4a9 |
| Source note | uspto-grants-2016_05 |