HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-chlorobutyramide → N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-(2-pyridylthio)butyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-chlorobutyramide | HCID 67726214 | — |
| Reactant | HCID 178418616 | HCID 178418616 | — |
| Product | N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-(2-pyridylthio)butyramide | HCID 67725994 | 53% |
Reaction Steps
Following a procedure similar to that described in Example 34, but using N-[4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenyl]-4-chlorobutyramide (prepared as described in Preparation 2) and 2-mercaptopyridine as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as an oil in a 53% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616579 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-e07dd7275ae142a087005e26d2ce40e0 |
| Source note | uspto-grants-1997_04 |