2-Amino-4-chlorobenzenethiol → HCID 57378423, compound

HRID 520913Notes

Reaction equation

HRID 520913 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[SH:9].[CH3:10][N:11]([CH3:16])[C:12](=[O:15])[CH:13]=[CH2:14].[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([S:24](Cl)(=[O:26])=[O:25])=[CH:20][C:19]=1[C:28]([F:31])([F:30])[F:29]>>[Cl:8][C:6]1[CH:5]=[CH:4][C:3]([S:9][CH2:14][CH2:13][C:12]([N:11]([CH3:16])[CH3:10])=[O:15])=[C:2]([NH:1][S:24]([C:21]2[CH:22]=[CH:23][C:18]([Cl:17])=[C:19]([C:28]([F:31])([F:29])[F:30])[CH:20]=2)(=[O:26])=[O:25])[CH:7]=1

Participants

4

Reactant 3

HCID 120002-Amino-4-chlorobenzenethiolHCID 17587N,N-DimethylacrylamideHCID 27807194-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride

Product 1

HCID 57378423HCID 57378423, compound

Procedure

Following General Procedure H, B, the title compound was prepared from 2-amino-4-chloro-benzenethiol, N,N-dimethyl-acrylamide, and 4-chloro-3-trifluoromethyl-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-5e41b97959fb4338ad3ae61cb9af0b55
Source dataset
uspto-grants-2016_05
Patent number
US09328067B2

Reaction notes

Loading…