HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 4-Amino-3-(benzylthio)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Amino-3-sulfanylbenzonitrile | HCID 15543936 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Amino-3-(benzylthio)benzonitrile | HCID 86690990 | 79% |
Reaction Steps
Following General Procedure A, the title compound (615 mg, 79%) was prepared from 4-amino-3-mercaptobenzonitrile (486 mg, 3.24 mmol), (bromomethyl)benzene (0.38 ml, 3.24 mmol) and K2CO3 (2.2 g, 16.20 mmol) in DMF (10 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328067B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-67a458b697184d88a553dbe54147052f |
| Source note | uspto-grants-2016_05 |