HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → Methyl 2-(((2-amino-5-chlorophenyl)thio)methyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Methyl 2-(((5-chloro-2-nitrophenyl)thio)methyl)benzoate | HCID 86691004 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Methyl 2-(((2-amino-5-chlorophenyl)thio)methyl)benzoate | HCID 82976200 | 106.9% |
Reaction Steps
Following General Procedure L, the title compound (158 mg, crude) was prepared from methyl 2-(((5-chloro-2-nitrophenyl)thio)methyl)benzoate (163 mg, 0.48 mmol), Zn (780 mg, 12.0 mmol) and saturated aqueous NH4Cl (10 ml) in MeOH (5 ml) and THF (5 ml). The crude product was used in the next reaction without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328067B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-a18d776c880d49c5a18c05ae2c782394 |
| Source note | uspto-grants-2016_05 |