HuagongsheHuagongshe Chemistry Print Report · For research reference only
10-Bromo-5,6-dihydro-benzo[f]quinoline → 10-(4-Methoxy-benzyl)-5,6-dihydro-benzo[f]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 10-Bromo-5,6-dihydro-benzo[f]quinoline | HCID 58294583 | — |
| Reactant | HCID 178490612 | HCID 178490612 | — |
| Product | 10-(4-Methoxy-benzyl)-5,6-dihydro-benzo[f]quinoline | HCID 58294391 | 85% |
Reaction Steps
The title compound is prepared from 4-methoxybenzylzinc chloride and 10-bromo-5,6-dihydro-benzo[f]quinoline following a procedure analogous to that described in Step 1 of Intermediates 21 and 22. Yield: 85% of theory; LC (method 1): tR=3.09 min; Mass spectrum (ESI+): m/z=302 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328072B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-ea8798bda46a49f4be8b503fb69fa96e |
| Source note | uspto-grants-2016_05 |