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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52100Generated: October 25, 2026

1,4-Oxathian-2-one → N-[5-(4-Piperidinomethyl-2-pyridyloxy)pentyl]-2-(2-hydroxyethylthio)acetamide

https://huagongshe.com/reaction/52100

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Oxathian-2-oneHCID 351060—
Reactant5-(4-Piperidinomethyl-2-pyridyloxy)pentylamineHCID 19962960—
ProductN-[5-(4-Piperidinomethyl-2-pyridyloxy)pentyl]-2-(2-hydroxyethylthio)acetamideHCID 1996290378%

Reaction Steps

Following a procedure similar to that described in Example 68, but using 5-(4-piperidinomethyl-2-pyridyloxy)pentylamine and 1,4-oxathian-2-one as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as an oil in a 78% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616579
Source datasetuspto-grants-1997_04
ORD IDord-8463a783272e498a913f45b8e4db18a2
Source noteuspto-grants-1997_04