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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52112Generated: October 25, 2026

1,4-Oxathian-2-one → N-[4-(4-Dimethylaminomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamide

https://huagongshe.com/reaction/52112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Oxathian-2-oneHCID 351060—
Reactant4-(4-Dimethylaminomethyl-2-pyridyloxy)-cis-2-butenylamineHCID 13672479—
ProductN-[4-(4-Dimethylaminomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamideHCID 6772580753%

Reaction Steps

Following a procedure similar to that described in Example 68, but using 4-(4-dimethylaminomethyl-2-pyridyloxy)-cis-2-butenylamine and 1,4-oxathian-2-one as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a 53% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616579
Source datasetuspto-grants-1997_04
ORD IDord-f37fbe5f088f4ce5998302782341a4c9
Source noteuspto-grants-1997_04