HCID 67222831, compound → HCID 178519365, compound

HRID 521133Notes

Reaction equation

HRID 521133 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[NH:13]1[CH2:18][CH2:17][CH2:16][C@@H:15]2[C:19]3[CH:20]=[CH:21][C:22]([OH:26])=[CH:23][C:24]=3[CH2:25][C@H:14]12>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:13]3[CH2:18][CH2:17][CH2:16][C@@H:15]4[C:19]5[CH:20]=[CH:21][C:22]([OH:26])=[CH:23][C:24]=5[CH2:25][C@H:14]34)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 67222831HCID 67222831, compoundHCID 178524171HCID 178524171, compound

Product 1

HCID 178519365HCID 178519365, compoundYield 18%

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and cis-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridin-7-ol following a procedure analogous to that described in Example 1. Yield: 18% of theory; LC (method 1): tR=1.97 min; Mass spectrum (ESI+): m/z=334 [M+H]+.

Sources & evidence

ORD record
ord-21701d7f9fa2439989019135ff065af8
Source dataset
uspto-grants-2016_05
Patent number
US09328072B2

Reaction notes

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