HCID 58294524, compound → HCID 178519353, compound

HRID 521164Notes

Reaction equation

HRID 521164 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[C:13]1([C:19]2[CH:20]=[CH:21][C:22]3[CH2:23][C@H:24]4[C@@H:29]([C:30]=3[CH:31]=2)[CH2:28][CH2:27][CH2:26][NH:25]4)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:25]3[CH2:26][CH2:27][CH2:28][C@@H:29]4[C:30]5[CH:31]=[C:19]([C:13]6[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=6)[CH:20]=[CH:21][C:22]=5[CH2:23][C@H:24]34)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 58294524HCID 58294524, compoundHCID 178524171HCID 178524171, compound

Product 1

HCID 178519353HCID 178519353, compoundYield 63%

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and cis-6-phenyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine following a procedure analogous to that described in Example 1. Yield: 63% of theory; LC (method 1): tR=3.28 min; Mass spectrum (ESI+): m/z=394 [M+H]+.

Sources & evidence

ORD record
ord-142192628bd54c2997768af97197023e
Source dataset
uspto-grants-2016_05
Patent number
US09328072B2

Reaction notes

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