HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86729357, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl 4-(cyanomethylidene)piperidine-1-carboxylate | HCID 15326949 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86729357 | HCID 86729357 | — |
Reaction Steps
tert-Butyl 4-(cyanomethylene)piperidine-1-carboxylate (5.0 g, 22 mmol) was dissolved in DCM (75.0 mL). TFA (8.7 mL, 112 mmol) was added, and the resulting mixture was allowed to stir at ambient temperature for 2 hours. The mixture was concentrated in vacuo to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328099B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-5e836a1d40e54e038c2fad3e0c807d34 |
| Source note | uspto-grants-2016_05 |