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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52120Generated: October 26, 2026

Butyryl chloride → N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-butyryloxyethylthio)acetamide

https://huagongshe.com/reaction/52120

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyryl chlorideHCID 8855—
ReactantN-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamideHCID 67725880—
ProductN-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-butyryloxyethylthio)acetamideHCID 6772583088%

Reaction Steps

Following a procedure similar to that described in Example 7, but using N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamide (prepared as described in Example 1) and butyryl chloride as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in an 88% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616579
Source datasetuspto-grants-1997_04
ORD IDord-6c8987d5d7ad4dd3b957641adaa52506
Source noteuspto-grants-1997_04