HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-dimethyl-1H-pyrrole-2-carboxylic acid → N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-3,5-dimethylpyrrole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-dimethyl-1H-pyrrole-2-carboxylic acid | HCID 2776468 | — |
| Reactant | 2-Buten-1-amine, 4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-, (Z)- | HCID 13672473 | — |
| Product | N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-3,5-dimethylpyrrole-2-carboxamide | HCID 67725857 | 58% |
Reaction Steps
Following a procedure similar to that described in Example 13, but using 4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenylamine and 3,5-dimethylpyrrole-2-carboxylic acid as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as crystals, melting 140°-141° C., in a 58% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616579 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-f43412afd4bc4d6098e24a8e03ff5350 |
| Source note | uspto-grants-1997_04 |