HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 68873567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | beta-Alanine, ethyl ester, hydrochloride | HCID 458475 | — |
| Reactant | 4-Chloro-3-nitroquinoline | HCID 11275808 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68873567 | HCID 68873567 | 98.8% |
Reaction Steps
The general method described in Step 1 of Example 1 was used to react 4-chloro-3-nitroquinoline (45.3 g, 217 mmol), β-alanine ethyl ester hydrochloride (40.0 g, 240 mmol), and triethylamine (54.8 g, 542 mmol) in dichloromethane for 15 hours to provide ethyl 3-(3-nitroquinolin-4-ylamino)propionate (62.0 g) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328110B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-20bec0a9e12749f182348792be3fd206 |
| Source note | uspto-grants-2016_05 |