2,2,3,3-Tetramethylcyclopropanecarboxylic acid → HCID 89669521, compound

HRID 521425Notes

Reaction equation

HRID 521425 reaction equation
[O:1]=[C:2]1[C:11]2[CH2:10][CH2:9][NH:8][CH2:7][C:6]=2[NH:5][C:4]2[CH:12]=[CH:13][CH:14]=[C:15]([C:16]([O:18][CH3:19])=[O:17])[C:3]1=2.[CH3:20][C:21]1([CH3:29])[C:23]([CH3:25])([CH3:24])[CH:22]1[C:26](O)=[O:27]>>[O:1]=[C:2]1[C:11]2[CH2:10][CH2:9][N:8]([C:26]([CH:22]3[C:23]([CH3:25])([CH3:24])[C:21]3([CH3:29])[CH3:20])=[O:27])[CH2:7][C:6]=2[NH:5][C:4]2[CH:12]=[CH:13][CH:14]=[C:15]([C:16]([O:18][CH3:19])=[O:17])[C:3]1=2

Participants

3

Reactant 2

HCID 1521152,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 89657239HCID 89657239, compound

Product 1

HCID 89669521HCID 89669521, compound

Procedure

The product was prepared from methyl 5-oxo-1,2,3,4,5,10-hexahydrobenzo[b][1,7]naphthyridine-6-carboxylate and 2,2,3,3-tetramethyl cyclopropanecarboxylic acid according to the same procedure described as in Example 16 (step 1)

Sources & evidence

ORD record
ord-2299b4ac9f254aedb05af275efaba163
Source dataset
uspto-grants-2016_05
Patent number
US09328111B2

Reaction notes

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