HCID 67076259, compound → HCID 67076770, compound

HRID 521496Notes

Reaction equation

HRID 521496 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([NH2:16])[CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7]1=[O:15])=[O:5])[CH3:2].[CH3:17][O:18][C:19]1[CH:27]=[CH:26][C:22]([C:23](O)=[O:24])=[CH:21][C:20]=1[O:28][CH2:29][CH2:30][C:31]1[CH:32]=[C:33]([CH3:37])[CH:34]=[CH:35][CH:36]=1>>[CH2:1]([O:3][C:4]([C:6]1([NH:16][C:23](=[O:24])[C:22]2[CH:26]=[CH:27][C:19]([O:18][CH3:17])=[C:20]([O:28][CH2:29][CH2:30][C:31]3[CH:32]=[C:33]([CH3:37])[CH:34]=[CH:35][CH:36]=3)[CH:21]=2)[CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7]1=[O:15])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 67076259HCID 67076259, compoundHCID 67076769HCID 67076769, compound

Product 1

HCID 67076770HCID 67076770, compound

Procedure

2-Amino-1-oxo-indane-2-carboxylic acid ethyl ester (L. Benati et al., J. Org. Chem. 64 (1999), 7836-7841) (460 mg, 2.10 mmol) was reacted with 4-methoxy-3-(2-m-tolyl-ethoxy)-benzoic acid in analogy to step 2 of example 13 to yield 0.331 g of the title compound.

Sources & evidence

ORD record
ord-51185aea0ede4399977954b638dcfb4c
Source dataset
uspto-grants-2016_05
Patent number
US09328071B2

Reaction notes

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