methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochloride → HCID 67076809, compound

HRID 521499Notes

Reaction equation

HRID 521499 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([C:10]2[C:11]([O:19][CH3:20])=[N:12][CH:13]=[C:14]([CH:18]=2)[C:15]([OH:17])=O)[CH:7]=[CH:8][CH:9]=1)([CH3:3])[CH3:2].Cl.C[O:23][C:24]([C:26]1([NH2:35])[CH2:34][C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH2:27]1)=[O:25]>>[CH:1]([C:4]1[CH:5]=[C:6]([C:10]2[CH:18]=[C:14]([C:15]([NH:35][C:26]3([C:24]([OH:25])=[O:23])[CH2:27][C:28]4[C:33](=[CH:32][CH:31]=[CH:30][CH:29]=4)[CH2:34]3)=[O:17])[CH:13]=[N:12][C:11]=2[O:19][CH3:20])[CH:7]=[CH:8][CH:9]=1)([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 45074056methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochlorideHCID 67076808HCID 67076808, compound

Product 1

HCID 67076809HCID 67076809, compound

Procedure

The compound of step 2 was reacted with 2-amino-indane-2-carboxylic acid methyl ester hydrochloride in analogy to step 2 of example 13, and the obtained ester hydrolyzed in analogy to example 2.

Sources & evidence

ORD record
ord-deb1cf32c0314ef6995273e57e273804
Source dataset
uspto-grants-2016_05
Patent number
US09328071B2

Reaction notes

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