HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Phenyloxetan-3-yl)methanol → 2-[4-Methoxy-3-(3-phenyl-oxetan-3-ylmethoxy)-benzoylamino]-indane-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Phenyloxetan-3-yl)methanol | HCID 20063137 | — |
| Reactant | 2-(3-Hydroxy-4-methoxy-benzoylamino)-indane-2-carboxylic acid methyl ester | HCID 67076518 | — |
| Product | 2-[4-Methoxy-3-(3-phenyl-oxetan-3-ylmethoxy)-benzoylamino]-indane-2-carboxylic acid | HCID 67076801 | — |
Reaction Steps
The compound of step 2 of example 15 and (3-phenyl-oxetan-3-yl)-methanol (S. Kanoh et al., Tetrahedron 58 (2002), 7065-7074) were reacted in analogy to step 3 of example 15, and the obtained methyl ester was hydrolyzed in analogy to example 16.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328071B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-7eadf9c3682743548d38d98124342153 |
| Source note | uspto-grants-2016_05 |