Methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate → 2-[3-Methoxy-4-(2-m-tolyl-ethoxy)-benzoylamino]-indane-2-carboxylic acid

Participants

Role	Name	HCID	Charge
Reactant	Methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate	HCID 45074057	—
Reactant	HCID 67076777	HCID 67076777	—
Product	2-[3-Methoxy-4-(2-m-tolyl-ethoxy)-benzoylamino]-indane-2-carboxylic acid	HCID 67076688	—

Reaction Steps

The compound of step 3 was hydrolyzed in analogy to example 2, the obtained carboxylic acid reacted with 2-amino-indane-2-carboxylic acid methyl ester in analogy to step 1 of example 15, and the obtained ester hydrolyzed in analogy to example 2.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09328071B2
Source dataset	uspto-grants-2016_05
ORD ID	ord-3c89df55f5e542d59af03f889c67070e
Source note	uspto-grants-2016_05