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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 521695Generated: October 30, 2026

1,2-Dimethoxyethane → HCID 118034959, compound

https://huagongshe.com/reaction/521695

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
Reactant3-Bromo-1,1,1-trifluoro-2-propanoneHCID 79008—
Reactant4-Bromopyrimidin-2-amineHCID 12803496—
ProductHCID 118034959HCID 118034959—

Reaction Steps

A mixture of 1.14 g of 3-bromo-1,1,1-trifluoropropan-2-one and 10 ml of DME was added to a mixture of 1.04 g of 2-amino-4-bromopyrimidine and 10 ml of DME, and the mixture was stirred at room temperature for 1 day. The precipitated solid was taken by filtration, washed with 10 ml of DME, and dried to obtain 1.92 g of 7-bromo-2-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridin-2-ol hydrobromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328121B1
Source datasetuspto-grants-2016_05
ORD IDord-1dced3333f1f4a2c9ad392e2fae56b22
Source noteuspto-grants-2016_05