HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dimethoxyethane → HCID 118034959, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dimethoxyethane | HCID 8071 | — |
| Reactant | 3-Bromo-1,1,1-trifluoro-2-propanone | HCID 79008 | — |
| Reactant | 4-Bromopyrimidin-2-amine | HCID 12803496 | — |
| Product | HCID 118034959 | HCID 118034959 | — |
Reaction Steps
A mixture of 1.14 g of 3-bromo-1,1,1-trifluoropropan-2-one and 10 ml of DME was added to a mixture of 1.04 g of 2-amino-4-bromopyrimidine and 10 ml of DME, and the mixture was stirred at room temperature for 1 day. The precipitated solid was taken by filtration, washed with 10 ml of DME, and dried to obtain 1.92 g of 7-bromo-2-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridin-2-ol hydrobromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328121B1 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-1dced3333f1f4a2c9ad392e2fae56b22 |
| Source note | uspto-grants-2016_05 |