HRID521884

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cn1ncc([N+](=O)[O-])c1C1CCC(N=[N+]=[N-])C(O)CO1

HCID86713814

未命名化合物

结构：Cn1ncc([N+](=O)[O-])c1[C@@H]1CC[C@@H](N=[N+]=[N-])C(=O)CO1

HCID86713834

未命名化合物

PRODUCTS

生成物

结构：Cn1ncc([N+](=O)[O-])c1[C@@H]1CC[C@@H](N=[N+]=[N-])[C@@H](O)CO1

HCID86713835

未命名化合物

收率 74%

PROCEDURE

实验过程

Following the procedure for Intermediate 57 starting from (4R,7S)-4-azido-7-(2-methyl-4-nitro-pyrazol-3-yl)oxepan-3-one gave (3R,4R,7S)-4-azido-7-(2-methyl-4-nitro-pyrazol-3-yl)oxepan-3-ol as a dark orange oil (850 mg, 74%). 1H NMR (400 MHz, CDCl3) δ 8.02 (s, 1H), 5.68-5.60 (m, 1H), 4.24-4.14 (m, 3H), 4.01 (s, 3H), 3.72-3.58 (m, 1H), 2.45-2.31 (m, 1H), 2.30-2.09 (m, 2H), 2.01-1.81 (m, 2H).