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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 521897Generated: October 25, 2026

2-(3,5-Difluorophenyl)propan-2-ol → 2-(3,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

https://huagongshe.com/reaction/521897

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3,5-Difluorophenyl)propan-2-olHCID 57732159—
Reactant1-(3,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanolHCID 86713851—
Product2-(3,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-olHCID 70655156—

Reaction Steps

Following the procedure of Intermediate 106, replacing 1-(3,5-difluorophenyl)ethanol with 2-(3,5-difluorophenyl)propan-2-ol (see US2012/225062) provided the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328106B2
Source datasetuspto-grants-2016_05
ORD IDord-2d40828508a843f79da6c2e3b98e4bc9
Source noteuspto-grants-2016_05