HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → Thiophen-2-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 2-Thiopheneacetyl chloride | HCID 162362 | — |
| Product | Thiophen-2-acetamide | HCID 78208 | 64% |
Reaction Steps
To a mixture of concentrated NH4OH (100 mL) and ice was added 2-thiopheneacetyl chloride (13.0 g, 80.9 mmol). The desired compound crystallized from the reaction mixture. Recrystallization from hot water gave 2-thiopheneacetamide (8.08 g, 64% yield) as white crystals. mp 146°-147° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616596 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-d50cdad937b642df885f4e3877aa82ac |
| Source note | uspto-grants-1997_04 |