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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 521901Generated: October 25, 2026

(2-(Difluoromethyl)phenyl)boronic acid → 2-(2-(Difluoromethyl)phenyl)thiazole-4-carboxylic acid

https://huagongshe.com/reaction/521901

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-(Difluoromethyl)phenyl)boronic acidHCID 44717243—
Reactant2-(2,6-Difluoro-4-methoxyphenyl)thiazole-4-carboxylic acidHCID 83410043—
Product2-(2-(Difluoromethyl)phenyl)thiazole-4-carboxylic acidHCID 86713855—

Reaction Steps

Following the procedure of Intermediate 104, replacing 2,6-difluoro-4-methoxyphenylboronic acid with (2-(difluoromethyl)phenyl)boronic acid gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328106B2
Source datasetuspto-grants-2016_05
ORD IDord-bfcf490ec5674ee5a0a00ee421a24d5d
Source noteuspto-grants-2016_05