HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-fluorophenylboronic Acid → 2-(3-Chloro-2-fluorophenyl)thiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-fluorophenylboronic Acid | HCID 16217158 | — |
| Reactant | 2-(2,6-Difluoro-4-methoxyphenyl)thiazole-4-carboxylic acid | HCID 83410043 | — |
| Product | 2-(3-Chloro-2-fluorophenyl)thiazole-4-carboxylic acid | HCID 63034592 | — |
Reaction Steps
Following the procedure of Intermediate 104, replacing 2,6-difluoro-4-methoxyphenylboronic acid with (3-chloro-2-fluorophenyl)boronic acid gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328106B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-a63b7eb45fe84cd9ac9da2873e56a3c7 |
| Source note | uspto-grants-2016_05 |