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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 521911Generated: October 27, 2026

(2-Chloro-3-fluorophenyl)boronic acid → 2-(2-Chloro-3-fluorophenyl)thiazole-4-carboxylic acid

https://huagongshe.com/reaction/521911

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Chloro-3-fluorophenyl)boronic acidHCID 22309459—
Reactant2-(2,6-Difluoro-4-methoxyphenyl)thiazole-4-carboxylic acidHCID 83410043—
Product2-(2-Chloro-3-fluorophenyl)thiazole-4-carboxylic acidHCID 83318587—

Reaction Steps

Following the procedure of Intermediate 104, replacing 2,6-difluoro-4-methoxyphenylboronic acid with (2-chloro-3-fluorophenyl)boronic acid gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328106B2
Source datasetuspto-grants-2016_05
ORD IDord-aab714d220784f3992b8a4ac34e4f964
Source noteuspto-grants-2016_05