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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 521933Generated: October 30, 2026

HCID 70655139, compound → HCID 86713871, compound

https://huagongshe.com/reaction/521933

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 70655139HCID 70655139—
Reactant2-(2,6-Difluoro-4-methoxyphenyl)thiazole-4-carboxylic acidHCID 83410043—
ProductHCID 86713871HCID 86713871—

Reaction Steps

Following the procedure of Intermediate 104, replacing 2,6-difluoro-4-methoxyphenylboronic acid with 3-(3,5-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)tetrahydrofuran-3-ol (Intermediate 143) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328106B2
Source datasetuspto-grants-2016_05
ORD IDord-c37594e25bcc4ba0ad4d5ad4186572d5
Source noteuspto-grants-2016_05