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HRID522000

反应详情

EQUATION

反应方程式

HRID 522000 的结构方程式

REACTANTS

反应物

2
结构：COc1ncccc1B(O)O
HCID2762709

2-Methoxypyridine-3-boronic acid

C6H8BNO3

结构：Cn1ncc(NC(=O)c2csc(Br)n2)c1[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)[C@H](F)CO1
HCID86713845

未命名化合物

2 次

PRODUCTS

生成物

1
结构：COc1ncccc1-c1nc(C(=O)Nc2cnn(C)c2[C@@H]2CC[C@@H](N)[C@H](F)CO2)cs1
HCID73438525

未命名化合物

PROCEDURE

实验过程

Following the procedure for Example 101 starting from tert-butyl ((3S,4R,7S)-7-(4-(2-bromothiazole-4-carboxamido)-1-methyl-1H-pyrazol-5-yl)-3-fluorooxepan-4-yl)carbamate (Intermediate 99), and replacing 3,6-dihydro-2H-pyran-4-boronic acid pinacol ester with (2-methoxypyridin-3-yl)boronic acid gave 232. LCMS (ES+) m/z 447 (M+1).