HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Fluoropyridin-2-yl)boronic acid → HCID 73437701, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Fluoropyridin-2-yl)boronic acid | HCID 53401125 | — |
| Reactant | tert-butyl ((3S,4R,7S)-7-(4-(2-bromothiazole-4-carboxamido)-1-methyl-1H-pyrazol-5-yl)-3-fluorooxepan-4-yl)carbamate | HCID 86713845 | — |
| Product | HCID 73437701 | HCID 73437701 | — |
Reaction Steps
Following the procedure for Example 101 starting from tert-butyl ((3S,4R,7S)-7-(4-(2-bromothiazole-4-carboxamido)-1-methyl-1H-pyrazol-5-yl)-3-fluorooxepan-4-yl)carbamate (Intermediate 99), and replacing 3,6-dihydro-2H-pyran-4-boronic acid pinacol ester with (3-fluoropyridin-2-yl)boronic acid gave 237. LCMS (ES+) m/z 435 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328106B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-94cb936d46624111b967eb3d729d7a13 |
| Source note | uspto-grants-2016_05 |