HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-(2-chloro-5-(3-cyanopyridin-2-yl)benzamido)-N-cyclopropyl-1-phenyl-1H-pyrazole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloronicotinonitrile | HCID 81079 | — |
| Reactant | HCID 123184206 | HCID 123184206 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-(2-chloro-5-(3-cyanopyridin-2-yl)benzamido)-N-cyclopropyl-1-phenyl-1H-pyrazole-3-carboxamide | HCID 118497170 | — |
Reaction Steps
The title compound was prepared according to the method described for Example 83 using 5-(2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamido)-N-cyclopropyl-1-phenyl-1H-pyrazole-3-carboxamide in dioxane (Preparation 10) and 2-chloronicotinonitrile with potassium carbonate as base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328096B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-10dafa9d02c744ffa78d1a9e426b68e6 |
| Source note | uspto-grants-2016_05 |