Allyl bromide → HCID 118274153, compound

Participants

Reaction Steps

To an ice-cooled suspension of Example 153B (1 g, 7.99 mmol) and Cs2CO3 (3.91 g, 11.99 mmol) in N,N-dimethylformamide (10 mL) was added dropwise allyl bromide (1.06 g, 8.79 mmol), and the reaction was stirred at room temperature overnight. The reaction mixture was partitioned between water (100 mL) and ethyl acetate (3×40 mL). The organic extracts were dried (Na2SO4), filtered, and concentrated to give the title compound which was used without further purification. MS (ESI+) m/z 166.0 (M+H)+.

Provenance & Evidence