N-(3-chloropropyl)piperidine hydrochloride → HCID 89590854, compound

HRID 522392Notes

Reaction equation

HRID 522392 reaction equation
Cl.Cl[CH2:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1.[C:12]([C@H:16]1[C:43](=[O:44])[N:42]2[CH2:45][C@@H:39]([CH2:40][C@H:41]2[C:46]([O:48][CH3:49])=[O:47])[O:38][C:28]2=[N:29][C:30]3[CH:31]=[CH:32][CH:33]=[CH:34][C:35]=3[C:36]([OH:37])=[C:27]2[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][C@@H:21]2[CH2:50][CH2:51][CH2:52][C@H:20]2[O:19][C:18](=[O:53])[NH:17]1)([CH3:15])([CH3:14])[CH3:13]>>[C:12]([C@H:16]1[C:43](=[O:44])[N:42]2[CH2:45][C@@H:39]([CH2:40][C@H:41]2[C:46]([O:48][CH3:49])=[O:47])[O:38][C:28]2=[N:29][C:30]3[CH:31]=[CH:32][CH:33]=[CH:34][C:35]=3[C:36]([O:37][CH2:3][CH2:4][CH2:5][N:6]3[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]3)=[C:27]2[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][C@@H:21]2[CH2:50][CH2:51][CH2:52][C@H:20]2[O:19][C:18](=[O:53])[NH:17]1)([CH3:15])([CH3:13])[CH3:14]

Participants

3

Reactant 2

HCID 79624N-(3-chloropropyl)piperidine hydrochlorideHCID 178501305HCID 178501305, compound

Product 1

HCID 89590854HCID 89590854, compound

Procedure

The title compound was prepared using the same method as described in Example 42 using 1-(3-chloropropyl)piperidine hydrochloride as the alkylating agent with the product of Step 1. LRMS (ES+) m/z 707.5 (M+H)+.

Sources & evidence

ORD record
ord-c85caab1b130420c933c0e7c848f8dea
Source dataset
uspto-grants-2016_05
Patent number
US09328138B2

Reaction notes

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