Acetic Acid → HCID 117598871, compound

Participants

Reaction Steps

To a solution of the ester from Step 2 (55.8 mg) in THF (0.8 mL) and ethanol (0.2 mL) was added 2M LiOH (0.4 mL). After 1 hour at room temperature, the reaction was done. The mixture was diluted with ethyl acetate and water. Then, acetic acid was added until pH=5. The mixture was extracted with ethyl acetate (3×). The combined organics were dried over sodium sulfate, filtered and concentrated. LRMS (ES−) m/z 691.3 (M−H)−.

Provenance & Evidence