Tert-butyl 4-hydroxypiperidine-1-carboxylate → HCID 89590519, compound

Participants

Reaction Steps

The title compound was prepared using the same method as described in Example 210, Step 1 with methyl (1aR,5S,8S,10R,22aR)-5-tert-butyl-17-hydroxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoline-8-carboxylate (Example 113, Step 5) and 1-Boc-4-hydroxypiperidine. LRMS (ES+) m/z 737.5 (M+H)+.

Provenance & Evidence