HCID 86691612, compound → 1-[(6-fluoro-2-pyridinyl)methyl]-1H-pyrazol-3-amine

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Reaction Steps

Title compound was prepared by a method analogous to that described for Intermediate 47, replacing Intermediate 46 with Intermediate 45 (90 mg, 0.279 mmol) to yield the title compound (48 mg, 0.250 mmol, 48% yield). 1H NMR (300 MHz, CDCl3) δ ppm: 7.73 (q, 1H), 7.30 (d, 1H), 6.89 (dd, 1H), 6.83 (dd, 1H), 5.67 (d, 1H), 5.16 (s, 2H), 2.87 (br s, 2H). [ES+MS] m/z 192 (MH+).

Provenance & Evidence