反应详情

To a solution of tert-butyl 4-(5-benzoylpyrimidin-2-yl)piperazine-1-carboxylate (957 mg, 2.6 mmol) in dioxane (20 mL) was added 4 M HCl-dioxane (20 mL). The reaction mixture was stirred at room temperature overnight and concentrated to afford crude phenyl(2-(piperazin-1-yl)pyrimidin-5-yl)methanone which was used in the next step directly.

1. concentrationconcentrated