Iodoethane → HCID 67375894, compound

Participants

Reaction Steps

To a suspension of 2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole and NaH (1.1 equiv.) in DMF (10 mL) was added at 0° C., ethyl iodide (1 mmol) and stirred at RT overnight. The reaction mixture was quenched with a sat. solution of NH4Cl and extracted with EtOAc. The combined organic extracts were dried over anydrous Na2SO4 and purified by flash chromatography to afford 2-benzyl-5-ethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (85%).

Provenance & Evidence