Cyclohexene oxide → HCID 89995668, compound

HRID 523061Notes

Reaction equation

HRID 523061 reaction equation
[Cl:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([C:12]1[CH:13]=[N:14][NH:15][CH:16]=1)=[CH:7][CH:6]=2.[CH:17]12[O:23][CH:22]1[CH2:21][CH2:20][CH2:19][CH2:18]2>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([C:12]1[CH:16]=[N:15][N:14]([CH:21]3[CH2:20][CH2:19][CH2:18][CH2:17][CH:22]3[OH:23])[CH:13]=1)=[CH:7][CH:6]=2

Participants

3

Reactant 2

HCID 9246Cyclohexene oxideHCID 89995577HCID 89995577, compound

Product 1

HCID 89995668HCID 89995668, compound

Procedure

The title compound was prepared according to the method described for Preparation 45 using 3-chloro-6-(1H-pyrazol-4-yl)isoquinoline and 7-oxabicyclo[4.1.0]heptane.

Sources & evidence

ORD record
ord-bde72d6d108443c883b0ec3f2def87ef
Source dataset
uspto-grants-2016_05
Patent number
US09334286B2

Reaction notes

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